Endocannabinoid Deficiency Fibromyalgia: Is CBD the Answer?

Fibromyalgia has plagued the lives of many, both physically and emotionally. It causes disability and depression, making people feel isolated and unproductive. However, its cause, just like that of many other conditions, remains a mystery to sufferers and doctors… Could science be close to figuring it out?

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What is Fibromyalgia?

Fibromyalgia is a mysterious illness that causes sufferers to feel pain in their body for no apparent reason. It is more prevalent in women, and it is currently the most common rheumatology diagnosis in the United States.

Often, people who suffer from it are dismissed as being over dramatic, or some claim their pain to be psychosomatic, which is why the diagnosis is fairly new, compared to other conditions.

However, in recent years, studies have shown that fibromyalgia is, in fact, a very real medical condition that not only causes unnecessary pain signals to be sent to the brain, but also alters the pain threshold, making people a lot more sensitive to these signals, which is referred to as  hyperalgesia.

In sufferers, fibromyalgia causes stress, anxiety, feelings of guilt, isolation, and even disability. It is part of a group of conditions referred to as subjective pain syndromes, which are difficult to identify, since there are no objective, observable signs and they are often resistant to medical treatment. It is characterized by painful trigger points, mostly in the shoulders and neck, that limit physical activity and generate frustration.

It is associated closely with depression and anxiety, but it isn’t clear if one causes the other or if they coexist because they have the same origin.

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Endocannabinoid Deficiency?

In our bodies, the endocannabinoid system, or ECS, has two basic tasks:

  1. Balance feelings of well-being
  2. Stimulating the body to heal from injury or illness

This system reacts to endocannabinoids (cannabinoids that are naturally produced by our bodies), which interact with it and keep it running as it should.

Clinical endocannabinoid deficiency syndrome, CECD, happens when the concentration of these endocannabinoids, called anandamide and 2-AG, are lower than normal. This is a very new discovery, the initial theory having been proposed in 2001, and subsequent studies have backed it up.

Slowly, scientists and doctors are catching on to how this affects us, and have been shocked to discover that the effects are a lot broader and more significant than previously thought.

The origin of the theory came from the fact that many brain disorders are related to neurotransmitter deficiencies, so it was concluded that, considering its main function, chronic endocannabinoid deficiency should result in alterations in the sensations of pain, system imbalance and inflammation, since the endocannabinoid system plays an important role in those.

Conditions whose cause has been unknown for centuries now have a little ray of sunshine. Low levels of anandamide have been reported in people suffering from a number of illnesses whose cause was eluding the medical community.

If endocannabinoid deficiency proves to be the cause, these illnesses will now have better, more effective treatments that will make them more manageable, and they will be less likely to cause disability and depression.

Endocannabinoid Deficiency Fibromyalgia, Migraine, PTSD and IBS

Some of the conditions that have been observed to concur with clinical endocannabinoid deficiency are: fibromyalgia, migraines, PTSD and IBS, among others.

These three conditions have certain common characteristics:

  • Heightened sensitivity to pain, or hyperalgesia, which has been observed to be associated with endocannabinoid hypo-function (decreased function of the ECS).
  • Are accompanied by anxiety and depression
  • Have been labeled as psychosomatic
  • They coexist in the majority of cases, which suggests the same cause

Recently, it was discovered that people who suffer from fibromyalgia have a distinct deficiency of the endocannabinoid anandamide, which our body is supposed to produce naturally. Anandamide generates feelings of well-being and, in high amounts, can cause euphoria. However, if its concentration is too low, it has shown to have incredibly negative effects physically and emotionally.

When looking further into the issue, other illnesses were associated with this deficiency, which was officially named “clinical endocannabinoid deficiency syndrome,” or CECD. And the main conditions it has been related to often overlap, supporting the theory that it is the possible cause.

Endocannabinoid Deficiency Fibromyalgia: Is CBD the Answer?

If anandamide deficiency proves to be the cause of some or all cases of fibromyalgia, there is a lot of hope for a successful treatment to be developed and standardized in the near future.

CBD is a phytocannabinoid, a cannabinoid that is produced in plants, which stimulates CB2 receptors, the same type of receptors that react to anandamide and cause feelings of wellness and pain relief. Theoretically speaking, CBD should be able to replace anandamide in people who have low concentrations of it, until eventually the body is able to regulate its production.

Interestingly, in a specific study, CBD showed an improvement in fibromyalgia symptoms that highly surpassed those of the usual medications prescribed for this condition (like duloxetine and milnacipran).  

In fibromyalgia and other CECD related conditions, cannabinoid treatment, mainly CBD treatment, has shown improved sleep, pain relief, and other benefits that support the influence of the deficiency in the symptoms.

In a few trials, THC was studied as a possible treatment, but the results were not as significant as the ones showed for CBD and whole plant cannabis, which showed decreased pain and stiffness almost immediately, as well as improvement in sleep and reduced anxiety.

The use of cannabis-based epilepsy medication, Sativex also proved to be highly effective for pain, which proves that CBD oil for fibromyalgia is the best option.

What is the cause of endocannabinoid deficiency fibromyalgia?

Humans have an optimal level of endocannabinoids (anandamide and 2-AG) in the body, which interact with endocannabinoid receptors. When endocannabinoid function is lower than normal,a series of conditions will necessarily follow, such as:

  • Digestive issues
  • Mood alterations
  • Sleep alterations
  • General well-being will be disrupted

It is still unknown why these lower endocannabinoid levels occur, but the CED theory suggests that the cause could be genetic or congenital, or might even be acquired after a significant injury or illness that alters the balance of the endocannabinoid production.

Other illnesses that have been linked to CECD

The ones mentioned above are not the only conditions that seem to be linked to clinical endocannabinoid deficiency. Others that are being evaluated for their possible relation to CECD are:

  • Neonatal failure to thrive
  • Cystic fibrosis
  • Phantom limb pain
  • Infantile colic
  • Dysmenorrhea
  • Repetitive, unexplained miscarriages
  • PTSD
  • Bipolar disorder

These are just a few, though there are many others that could be part of this list.

Clinical endocannabinoid deficiency is new, but very important discovery being studied currently that could help us understand different conditions that have mostly been a complete mystery to us.

It seems almost obvious when you think about illnesses being caused by the body being unbalanced. A lot of people have spoken about CBD oil and fibromyalgia. However, we are so used to having external causes to our ailments, that we have failed to see what was right under our noses.

Our bodies have lost balance, so we need to return it to them in order to be healthier and feel better. Hopefully CBD treatments are standardized and recognized as valid methods of improving the quality of life of those who suffer from fibromyalgia and have seen their lives altered by it.

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How Cannabinoids are Responsible for Runner’s High

After running or working out, people experience a number of sensations. This is known as the runner’s high, and studies suggest it is produced because of a cannabinoid found in our own brain.

“Run, Forest! Run!” Remember that scene from that awesome and timeless movie? Forest escaping from those bullies in bikes, rushing to the end-zone or crossing the entire country with a beard while the crowd followed him. “I just felt like running”, he said in that unforgettable accent of his. After those metal supports came off his legs, he never stopped running.

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Well, the truth is that Forest Gump was high as a kite on endocannabinoids. And if you are a regular runner, you probably have experienced the same high as Forest. Psychologically, and according to WebMD, runners experience euphoria, a feeling of being invincible, a reduced state of pain or discomfort and even loss in sense of time while running.

This concept is known as runner’s high. Biologically speaking, running sets in motion a lot of chemical reactions that give that sensation of being unstoppable. For a long time, scientists thought endorphins were responsible for that high. However, studies found that there is a direct correlation between intense aerobic activity and the endocannabinoid system.

What is the Runner’s High?

Forest just sitting in his dock. Looking at the horizon with his Bubba Gump hat laying in his lap. Then something clicks in that mind of his. He gets up slowly and starts running. “That day, for no particular reason, I decided to go for a run. And for no particular reason, I just kept on going”. He ran all across his loving Alabama and continue all the way to the west coast.

During the last decade, running has become one of the most popular activities in the United States. According to Bureau of Labor Statistics, in 2003, only 15.9% of people 15 and older participated in some form of exercise. That number grew up to 20% in 2015. And if you don’t believe statistics, just take a look at your street or your nearest park in the morning. You are going to see a whole army of people with an armband, headphones and running shoes. And just like Forest, when does people start running, they just keep on going.

But, if you start to think about it, you have to ask the question. Why people like Forest and your neighbors are so into running? We can answer that. And no, the answer is not Jenny!

Endorphins

For decades, scientists have tried to figure out why exercise becomes so addictive for some people like Forest Gump. Some dare to say that it is as addictive as any other drug. Actually, it is not that far from the truth. During the 80’s, some studies concluded that there was a direct link between endorphins and running. Endorphins, in a very superficial definition, are the opioids that our bodies produce naturally.

Endorphins interact with several receptors in the brain that reduce perception of pain. Also, endorphins produce a positive feeling in our bodies. Endorphins can also be released during other physical activities, like sex. So when Jenny got into Forest’s bed, he also got high on endorphins. Naughty Forest.

But let us go back to running. A study published during early 1984 made a review on the evidence on exercise and endorphins. Among other findings, it concluded that there was significant evidence that endorphins “depress ventilation and play a role in ventilatory regulation”. This means that high levels of endorphins can change the perception of fatigue.

Furthermore, in 2009 a study explained how addictive exercise can become. Scientists concluded that, when taken to extremes, exercise can “develop into an addictive-like behavior”. Mice were submitted to exercise on a running wheel. They got so addicted to it that they showed a dependency similar to that observed in morphine dependant patients. Rats who went through high intensity running showed very severe withdrawal symptoms. There where even cases of mice that preferred running over eating to the point of even dying.

Recently, a new study came up. It suggested that endorphins were not the ones in charge of creating runner’s high. Another chemical compound created by our bodies came up: anandamide.

What is Anandamide?

Forest Gump was first released on June 23, 1994. Two years before that, halfway around the world, a couple of scientist discovered a chemical compound created in our brain. This chemical compound was proof that every human body produces its own cannabinoid. On March 24, 1992, Lumír Hanus, a Czech chemist, and William Devane, an American pharmacologist, isolated for the first time a cannabinoid produced in the human brain. They called it anandamide.

Hanus and Devane were working in the Hebrew University of Jerusalem. They were part of a team lead by Dr. Raphael Mechoulam, world’s leading scientist on cannabis.

Hanus and Devane called this new molecule Anandamide because of the Sanskrit word “ananda”, which means “joy, bliss or happiness”. Anandamide is also known as the “bliss molecule”. It is the mimetic twin of THC, another cannabinoid. Unlike anandamide, it is found in the cannabis plant and produces psychoactive effects. But what they do have in common is that they both activate CB1 and CB2 receptors in our brains. And most importantly, anandamide produces psychological and physical effects like euphoria and pain relief.

Although it is hard to believe director Robert Zemeckis knew anything about anandamide, his lead character is full of it throughout the movie. At the beginning, when we said that Forest was high on cannabinoids, we really meant it. It turns out that when Forest was running or playing ping pong like his life depended on it, anandamide was all over his brain. And remember that part when he was in Vietnam, running through the jungle trying to save Bubba and Lieutenant Dan, he screamed “something bit me!”? Well, maybe the reason why Forest didn’t feel that much pain when that bullet reached his buttucks was because of anandamide flowing through his brain.

Endocannabinoid System, Anandamide and Runner’s High

Because of the discovery of anandamide, scientists started to consider that endorphins were not the reason for the runner’s high. When you start jogging, playing ping pong or running all across the Vietnamese jungle, endorphins are not the reason for that feeling of euphoria. Anandamide is.

Twenty three years after Hanus and Devane isolated anandamide for the first time, German scientists made the link between the endocannabinoid system, anandamide and runner’s high. They proved, among other things, that endorphins had nothing to do with the “high”.

Goodbye endorphins, Hello Anandamide!

These German researchers observed in the study that endorphins can’t pass the blood-brain barrier. However, they also found high levels of an endocannabinoid called anandamide. Contrarily, anandamide could travel from blood to brain. They also found high levels of anandamide in people’s blood after running. Anandamide has two important effects that are directly involved with runner’s high: analgesic and anti anxiety effects.

The researchers proved this with mice that were acquainted to exercise in a running wheel. They divided that group into two: one group would continue to run for 5 hours per day, while the other one remained without exercise.

After this, scientists submitted the mice to different tests to measure and analyze anxiety, pain reception and sedation. Their findings showed that two of the endocannabinoid system receptors played a major role in runner’s high. When anandamide interacts with CB1 receptors, it inhibits anxiety. While CB1 and CB2 receptors both have a response on pain reduction.

To get back to Forest, maybe that’s why he was so calm in the middle of a war and how he managed to keep on running even though he was shot in the buttock.

Other scientists, this time from the Arizona’s School of Anthropology, measured the endocannabinoid system responses in humans, dogs and ferrets, before and after treadmill exercise. They wanted to compare non-cursorial mammals (mammals that don’t have limbs suitable for running) such as ferrets with cursorial mammals, like dogs and humans like Forest.

Their study showed that humans and dogs show an increase signaling of the Endocannabinoid System after exercise. On the contrary, ferrets don’t experience much change in their endocannabinoid system after running. These findings can explain why “humans and other cursorial mammals habitually engage in aerobic exercise despite the higher associated energy costs and injury risks”.

Forest Gump is high on anandamide

Running made Forest very happy. It got him from playing football to winning a congressional medal of honor. He crossed the whole country and, most importantly, made his mama really proud. And while he did all of that, his endocannabinoid system was working as hard as he did. Every time Forest runs, anandamide levels start rising in his brain, nervous system and endocannabinoid system.

It is not endorphins but cannabinoids the ones that provide that runner’s high. Studies prove that anandamide, our very own and self-produced cannabinoid, gives Forest and the millions of runners in the world that bliss, that joy and that high after exercising.

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Explaining the Endocannabinoid System in the Human Body

As more people learn about the positive therapeutic effects of cannabis, the role of the endocannabinoid system will also become more relevant in the lives of everyday people. Endocannabinoid system research is already becoming quite a popular topic in scientific circles. We can definitely expect to see more of this research in a mainstream light as the politics of cannabis becomes more popular.

One of the hidden benefits of introducing cannabis into the world of legitimate medicine goes beyond its personal benefits. As scientists began to understand how cannabis can help the body balance itself, naturally a new question began to arise: why is the body so receptive to the substance? There must be something within the body itself that allows it to respond positively.

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Endocannabinoids and the Systems of the Body

The endocannabinoid system (ECS) acts a lot like cannabis does. It supports the major body systems, including immune, circulatory, nervous, and GI. It acts like a police officer might, directing and monitoring many of the chemical responses and processes. When it works correctly, the body feels healthy and rested. The blood flows to the organs. The bones stay strong and healthy. The mind is relaxed. But, the body’s systems can sometimes fail from time to time. From diet to pollution, exposure to stress, they may start to break down. When one system isn’t working properly, it can cause a chain reaction that affects the other systems.

And when this happens, the ECS may not function the way it should. It may stop reacting to certain events or it may overreact to certain stimuli. For example, people who have an autoimmune disorder. The immune system mistakes the healthy cells and tissues for illness or injury. This makes it more difficult for the body to handle external and internal stress.

Cannabinoids and endocannabindoids also work to synthesize the various systems of the body. Because of these two systems, cell types that would otherwise have difficulty coordinating with each other able to communicate. For instance, when the body is injured, cannabinoids help to stabilize the nerve cell. This is also the system that will help to prevent excessive firing and call in immune cells so that the injury does not become too inflamed. Without the cannabinoid system on the job, the body would have to spend a great deal more energy calling three systems together in order to address a simple injury.

The endocannabinoid system actually works as a bridge between the mind and the body. It performs incredibly complex actions within the body’s immune system, organs and nervous system. The study of endocannabinoids in the body actually helps researchers understand how different states of consciousness can promote faster healing of certain diseases.

Cannabinoids also influence the way that the body behaves within the environment that surrounds it. Obviously, cannabinoids have the ability to alter human behavior. This is where you will find the stereotypes of weed smoking – open-mindedness, different patterns of thought, happiness and sharing with others. We are just beginning to find out why the body responds in this way, and the best part about the research is that all that happiness will soon be quantified scientifically.

Sometimes the ECS can get back on track with little more than a few days rest. But, if it’s taxed, a person will start to see long-term effects over time. Depression, digestion, or autoimmune disorders are just a few possibilities. If the ECS starts to break down, it can result in general pain or unexplained discomfort. When people take cannabis, it can have the effect of managing the ECS so that the user can get back to normal.

What are the Cannabinoid Receptors?

The word ‘cannabinoid’ refers to the active parts of cannabis. A cannabinoid receptor refers to the part of the cell that responds to the cannabinoid. The cannabinoid system in the human body consists of two main types of receptors: CB1 and CB2. These receptors refer to how the cells react to the two main parts of the cannabis: THC and CBD.

Cannabis consists of both CBD and THC. It’s possible to extract either one from the plant (either in part or completely). This is how the public ends up with a variety of cannabis products. CBD is the non-psychoactive part of cannabis, meaning it won’t make a person feel ‘high’. It may help relieve stress or depression, but it does not affect a person’s mental state.

THC is the psychoactive part of the plan and can make users feel anything from paranoid to silly. This is the most common stereotype associated with cannabis. But it is not always the one that people should remember. People use cannabis for a variety of reasons. They use it to relieve chronic pain or to help their anxiety.

The CB1 receptors are those that respond to THC, and the CB2 receptors are those that respond to CBD. Neither THC or CBD is addictive. Both can have positive results if taken in the right dosages. If there are more CB2 receptors in a specific part of the body, then it will react to CBD. If there are more CB1 receptors, then it will react to THC. The central nervous system is more likely to respond to THC. This makes THC a solid choice for people who suffer from PTSD or anxiety. The cannabinoids bind to the amygdala. The amygdala is the part of the brain that’s responsible for emotions.

The nerves that lie outside the brain and spinal cord have both types of receptors. In this case, it’s the receptors that are strongest that will determine if CBD or THC are appropriate. These special nerve cells (called the peripheral nervous system) favor CBD over THC. Many children and adults will take CBD to control seizures. That’s because CBD can regulate the nerves that cause the convulsions. A person can also find both types of receptors in the actual brain, though there are more CB1 than CB2 receptors. This fact explains why THC causes psychoactive effects in the brain.

Cannabis research is not complete by any stretch of the imagination. We still need a lot more information about what the ECS does and how cannabis can alter it. But, from what we can tell, cannabis has very positive effects on the ECS of many people. This can lead to positive results when taking it for a variety of conditions. As researchers learn more about the ECS, they’ll tell t how to use it to benefit the human body.

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CBD oil for dogs: 5 illnesses that can be treated with CBD

Cannabis, specifically CBD, is as good for dogs as it is for humans. As well as humans, dogs, cats and all vertebrate animals have an Endocannabinoid System. This means that the medicinal benefits of cannabinoids can also apply to animals.

Pain, inflammation, arthritis, anxiety, seizures and cancer can all be treated with CBD, both in humans and in dogs. Although there is a lack of scientific evidence, veterinarians and owners across the country share their experiences on how CBD really helped their dog.

Before we take a look at the top 5 benefits of CBD for your pet, let’s take a quick look at how big this pet market is getting in the United States.

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How Millennials are encouraging the Cannabis Pet Market

Statistics of Pet Owners in the United States

The American Pet Products Association (APPA) puts this love for fury and fluffy companions into numbers and statistics. On the 2017-2018 National Pet Owners Survey, the report stated that 68% of the population in the United States has a pet at home. And, unsurprisingly, dogs and cats are at the top of the list.

Out of that 68% of pet owners, 48% are dog owners, while 38% are cat owners. APPA’s report goes even further and gives a very interesting fact: Millennials represent 35% of pet owners. And they spend more money on their pets than any other generation ever.

During 2017, this generation spent more than 30 billion dollars on their pets. This huge amount of money includes all kinds of products and services like schools, daycare, clothes, toys, food, healthcare… And parties! The APPA report states that 23% of millennial dog owners have birthday parties for their own pets. This is just awesomely cute!

The general conclusion is that dogs, cats and any other animals at home, are not considered pets. They are family. And for family, you pretty much are willing to do everything. And medicinal cannabis is no exception.

CBD products for pets are trending

Pet owners talk a lot to each other. They share experiences, recommend veterinarians as well as food and pet friendly restaurants and hotels. And, as cannabis interest grows everyday in the United States, it turns out that CBD is the next trending topic for pet owners.

Just like it happens with cannabis for humans, there is a lot of anecdotal evidence when it comes to successful treatments for pets. And word travels fast with pet owners. Brian Tasker, director of sales for a company selling CBD products for pets, told Marijuana Business Magazine how they use the pet-lovers network across the United States and Canada to draw attention.

“People might have a high-stress, high-anxiety dog, then they give them CBD and within seven days they’re walking with them. It’s like a different animal. And people tell everyone they know”.

Therefore, CBD is trending on the internet. Pet owners hear someone talk about how great CBD is for their dog and they immediately start surfing the web for more information. During 2018, the search term “CBD for pets” has reached several peaks of popularity according to Google (see chart below). After people search “CBD for pets”, other related searches are “CBD Oil” and “pet store”. When people find out how much CBD really works, they want to find the nearest store.

Top CBD products for dogs in the US market

As you can see, the pet industry is a huge market for cannabis companies. Today, owners and their 4-legged companions have a great variety of products to choose from. Because THC is toxic for dogs, market has expanded CBD products from oils to edibles and creams.

The most popular ones are CBD Oils. Depending on your dog’s weight, you can administer from 1 to 3 droppers a day, depending of course on the product you are buying for your dog. The best way to give CBD Oil to your dog is to administer it directly under his tongue. CBD Oil capsules are a little bit harder to give to your dog, but it is always a good trick to just mix it up with your dog’s food. They will eat right away and won’t even notice it. Dosage in capsules can vary from 1 to 3 per day, depending on your dog’s weight.

Edibles are great because they now come in all different flavors and presentations. And dogs really love crackers. There’s even a CBD peanut-butter flavored edible! Most edibles don’t have more than 2mg of CBD, so dogs can have between 3 and 8 crackers, also depending on the weight. It is very important that you check the dosage and how to administer everytime you buy CBD for your dog.

Because of the increasing interest in cannabis products for pets, we give you the top 5 benefits of CBD for your pet. Enjoy!

Top 5 CBD benefits that can help your dog

Anxiety

Multiple studies have concluded that CBD is a great treatment for anxiety disorders in humans. And for dogs it can be just as good.

Although there is little to no scientific evidence and studies to support how CBD can help anxiety in dogs, testimonies from both owners and veterinarias reinforce the idea. Tim Shu is a veterinarian and founder of VetCBD, a company that produces CBD products for pets. Tim is both owner and doctor. He owns a 16 year old pit bull who suffered from severe anxiety. He explains in this blog how CBD Oil helped Tye calm down.

“It takes away the anxiety without causing any state of disorientation or dizziness. I am able to take her outside while the fireworks are still going on”.

Dogs are prone to suffering from all kinds of anxiety. Fireworks and thunderstorms are not the only triggers. Dogs can also suffer from anxiety when separated from their owners too. Traveling and having new people in the house can also trigger some of the anxiety symptoms. These symptoms can be trembling, aggression, heavy barking, panting and fidgeting. Also chewing of furniture, shoes and other objects may be an indication of anxiety. In the most severe cases, a dog can become aggressive.

For example, dogs that have suffered violence tend to be more susceptible to anxiety. On VetCBD, a testimony of a happy owner told how CBD oil helped a pug named Kane:

“We are a rescue foundation and Kane was one of our dogs that was returned 3 times because adopters could not control his anxiety. My wife and I decided that we would just add him to our home and no longer try to place him. I purchased (a CBD Oil) and it worked like a charm. He actually calmed down and finally started enjoying his life!”

Seizures

Symptomatic seizures are normally caused by things happening both inside the brain, like encephalitis, or outside the brain, like lead poisoning or a head trauma. Idiopathic epilepsy, however, has no cause and it can be genetic. Some breeds are more prone to suffering from this type of epilepsy, like german shepherds, collies and border dogs. Other breeds like golden retrievers have a higher chance of suffering seizures.

Traditional medication can produce side effects like lethargy, confusion and liver damage. However, CBD, just like in humans, is one of the most powerful anticonvulsant. But just like it happens with anxiety, scientific evidence on pets is hard to find. We have to rely on testimonies from doctors and owners.

Dr. Gary Ritcher is a veterinarian from Oakland, and he tells the story of how CBD helped his dog. Leo got attacked by another dog. Poor Leo ended up with his jaw broken in several places and underwent two surgeries. After a couple of months, Leo started having seizures. Dr. Ritcher tried almost every medication available until he decided to try CBD. The result was amazing:

“Almost immediately, his seizure frequency decreased. He went from having multiple seizures per week to having one or two per month. It was immediate and there was really no doubt about the difference that it made all along. It never affected his quality of life in a negative way”.

On July 2018, researchers from the Colorado State University published preliminary results on a clinical trial to test the use of CBD in dogs with epilepsy. “Overall, what we found seems very promising,” said. Dr. Stephanie McGrath, one of the scientists involved in the study. This will be the first clinical trial that can prove all that anecdotal evidence on how can CBD help seizures in dogs.

Arthritis and Pain

Scientific evidence in sight! The first and only clinical trial made on CBD and dogs was published on July 2018. The study, titled “Pharmacokinetics, Safety, and Clinical Efficacy of Cannabidiol Treatment in Osteoarthritic Dogs”, was lead by Dr. Joseph Dr. Joseph Wakshlag of Cornell University.

Along with a group of scientists, Dr. Wakshlag measured the effects of a CBD based product on pain and arthritis. The study concluded that 2mg/kg of CBD twice a day can “help increase comfort and activity in dogs suffering from osteoarthritis”. More than 80% of the dogs that participated in the study experienced a decrease in pain and also improved their mobility.

This means that, for the first time, the veterinarian community has strong and clinical evidence to support how CBD can help reduce pain and help other symptoms associated with arthritis.

Cancer symptoms

One of the most painful news for dog owners is cancer. According to the Veterinary Cancer Society, the leading cause of death in dogs is cancer. The most common types in dogs are skin cancer, lymphoma, testicular cancer, abdominal cancer and bone cancer.

Cannabis benefits in human patients are reported in several studies. Some preliminary findings suggest that some cannabinoids even have anti-tumor properties for breast cancer. However, there’s still a long way to go. Cannabinoids have been used mainly to treat some of the symptoms cancer produces, like pain and lack of appetite associated with chemotherapy.

In dogs, chemotherapy can produce vomiting, diarrea, loss of appetite, hair loss in some cases, and nerve pain. But, unlike humans, chemotherapy for dogs is far less intrusive, and side effects are not as hard.

Blake Armstrong is the owner of Cannabis Supplements for Pets. He started his blog after his dog Rosie was diagnosed with cancer. And when he saw the results CBD had on his Rosie, he became a believer and defender of cannabis for pets.

After chemotherapy, Rosie lost her appetite, causing her weight to drop, and was in a very sad mood. But after trying CBD, Blake was “astounded by the results”, which he shared on his blog: “CBD helped my Rosie maintain a healthy appetite, and also helped her deal with the pain and inflammation caused by her hip dysplasia”.

Final recommendations

There is a lot of testimonial evidence that supports how CBD can be good for your pet. It can help anxiety, pain, arthritis and even cancer related symptoms. But, every dog is different, and they will react differently to CBD. All of the information above sounds very promising, and if you have a dog at home that can be treated with CBD, it is always recommended that you give your veterinarian a call.

Although CBD is harmless for dogs, THC can be very toxic. Choose your products carefully and always double check with your vet.

Also, be very mindful of your State’s cannabis legislation. Not all of the states have legalized medicinal cannabis, and most veterinarians are prohibited to prescribe cannabis based medication. Also, traveling across borders with cannabis products can really get you in trouble. So, if your dog is sick it won’t help at all if you end up in trouble.

If you keep these things in mind, there is no doubt that CBD is definitely going to help your furry friend.

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